Research Associate Vacancy in Computer Aided Drug Design at Institute of Life Sciences Hyderabad

Applications are invited for the following Research Associate position in Computer-Aided Drug
Discovery (CADD) group to work on the DST funded project, “Design, Synthesis, and Biological
Evaluation of Pharmaceuticallly Acceptable PTP-1B inhibitors”.

Research Associate
Fellowship: `22000 (basic) + 6600 (HRA) + 1833 (MR) = ` 30433 (fixed per month) inclusive all benefits for two years.
Duration: TWO year fixed from the date of joining

Responsibilities: The candidate will be performing molecular modeling studies assigned in the
project - designing, validating, and analyzing (a) SAR activities (b) protein-ligand interactions in
collaboration with the medicinal chemists and molecular biologists/pharmacologists. Main
responsibilities include computational studies and rational drug discovery applications. These studies
also include literature search, proper design and performing documentation, report and presentation
generation etc.

Essential Qualifications: (A) Ph.D. from a recognized university/institute in Computational
Chemistry/Biology with drug discovery principles as part of research work, or (B) Masters with
Pharmacy or Science (organic/physical chemistry) from a recognized university/institute with a
minimum 3-year research experience in relevant molecular modeling applications in drug discovery
setting is minimally required. Extensive applicative/usage knowledge in any drug discovery packages
such as BioSuite, Discovery Studio, GOLD, MDS, MOE, Schrodinger, SYBYL, MDS, and Sybyl is
highly essential; and, working experience with other cheminformatics packages like ACD/Labs etc. is
highly desirable. Working in team-environment with high morale is essential. Experience in
evaluation of protein-ligand interactions through docking, scoring, QSAR, SAR methods is essential.
Educational or applied synthetic organic chemistry knowledge with reaction mechanisms is beneficial.
Candidate should have extensive proficiency with Unix, Linux, Windows operating systems, MS office
products, and should be able to troubleshoot the HW/SW issues. He/She would be involved in
training medicinal chemists or early stage molecular modelers of the group in computational aspects.

Research Experience: More than 3 years with Masters’ degree or Ph.D in computer aided drug
discovery.

Interested candidates should send their curriculum vitae with a cover letter via e-mail to hr@ilsresearch.org and sreedhara.voleti@ilsresearch.org . Suitable candidates will be invited for an interview at the Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad – 500046. The location of the work is full-time at the ILS.

Notes:
• Visit the ILS website (www.ilsresearch.org) to obtain in-depth information about the institute
• Applicants should note that the appointments are purely temporary and there will be no right to
claim for any regular appointment
• The initial appointment will be made for one year and this could further be extended to one
more year based on the work progress
• No TA/DA will be paid to participate in the interview process or to join the institute

Last Date: no later than 30th October, 2010

Website Details: http://www.ilsresearch.org/

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